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• Naturforsch C J Biosci. 2018 Jul Shape-controlled synthesis of three-dimensional zinc oxide nanoflowers for disinfection of food pathogens

  The antibacterial activity of zinc oxide (ZnO) nanoflowers has been investigated and presented in this article. Classic three-dimensional nanoflowers have been prepared by hydrothermal method using zinc acetate dihydrate Zn(CH3COO)2·2H2O as the sole precursor. The X-ray diffraction and Fourier transform infrared spectra confirm the formation of ZnO crystals. Consequently, on the basis of morphological and… Read Abstract

• Int J Nanomedicine. 2014 Dec Biokinetics of zinc oxide nanoparticles: toxicokinetics, biological fates, and protein interaction

  Biokinetic studies of zinc oxide (ZnO) nanoparticles involve systematic and quantitative analyses of absorption, distribution, metabolism, and excretion in plasma and tissues of whole animals after exposure. A full understanding of the biokinetics provides basic information about nanoparticle entry into systemic circulation, target organs of accumulation and toxicity, and elimination time, which is important for… Read Abstract

• Int J Nanomedicine. 2014 Dec Prenatal development toxicity study of zinc oxide nanoparticles in rats

  This study investigated the potential adverse effects of zinc oxide nanoparticles ([ZnO(SM20(+)) NPs] zinc oxide nanoparticles, positively charged, 20 nm) on pregnant dams and embryo-fetal development after maternal exposure over the period of gestational days 5-19 with Sprague-Dawley rats. ZnO(SM20(+)) NPs were administered to pregnant rats by gavage at 0, 100, 200, and 400 mg/kg/day.… Read Abstract

• Nanotoxicology. 2010 Mar Zinc oxide nanoparticles in modern sunscreens: an analysis of potential exposure and hazard

  Sunscreens containing metal oxide nanoparticles appear transparent on the skin and provide excellent protection against sunburn caused by UV radiation. While it is likely that nanoparticles remain on the surface of the skin of healthy adult humans, and thus are considered safe for use in sunscreens, there has been no comprehensive assessment of the impact… Read Abstract

• J Colloid Interface Sci. 2019 Jul Zinc oxide/vanadium pentoxide heterostructures with enhanced day-night antibacterial activities

  Low photocatalytic efficiency of visible light and fast recombination of photo-generated carriers are two challenges facing the applications of photocatalyst sterilant zinc oxide (ZnO). Meanwhile, both light and dark photocatalytic activities are important. It is of great theoretical and practical significance to construct a day-night photocatalytic antibacterial material, which is beneficial to the effective use… Read Abstract

• Toxicol Ind Health. 2018 Nov Synthesis, characterization, and pharmacological evaluation of zinc oxide nanoparticles formulation

  Zinc oxide nanoparticles (ZnONPs) are being used extensively in manufacturing skin lotions and food products and in various biological and pharmaceutical industries because of their immunomodulatory and antimicrobial properties. In this study, ZnONPs were synthesized by a precipitation method and characterized by X-ray diffraction (XRD) techniques, scanning electron microscopy (SEM), and ultraviolet-visible spectroscopy to investigate… Read Abstract

• Expert Opin Drug Deliv.. 2010 Sep Zinc oxide nanoparticles for selective destruction of tumor cells and potential for drug delivery applications

  Importance of the field: Metal oxide nanoparticles, including zinc oxide, are versatile platforms for biomedical applications and therapeutic intervention. There is an urgent need to develop new classes of anticancer agents, and recent studies demonstrate that ZnO nanomaterials hold considerable promise. Areas covered in this review: This review analyzes the biomedical applications of metal oxide and ZnO… Read Abstract

• Drug Discov Today.. 2017 Dec Zinc oxide nanoparticles: a promising nanomaterial for biomedical applications

  Zinc oxide (ZnO) nanoparticles (NPs) are a promising platform for use in biomedical research, especially given their anticancer and antimicrobial activities. These activities are associated with the ability of ZnO NPs to generate reactive oxygen species (ROS) and induce apoptosis. In addition, ZnO NPs have been successfully exploited as drug carriers for loading and transporting… Read Abstract

• Life Sci.. 2019 Dec The current and future perspectives of zinc oxide nanoparticles in the treatment of diabetes mellitus

  Diabetes mellitus (DM) is a multifaceted and costly disease, which requires serious attention. Finding a cheaper anti-diabetic alternative that can act on multiple disease-related targets and pathways is the ultimate treatment goal for DM. Nanotechnology has offered some exciting possibilities in biomedical and drug delivery applications. Zinc oxide nanoparticles (ZnO-NPs), a novel agent to deliver… Read Abstract

• Crit Rev Toxicol.. 2016 Jan The toxicology of ion-shedding zinc oxide nanoparticles

  Zinc oxide nanoparticles (ZnO NPs) are nanomaterials that are widely used in many fields. ZnO NPs are ion-shedding particles, and zinc ions produce important and potent effects that differ from those of other metal or metal oxide NPs. Several studies have reported the toxicological effects of ZnO NPs administered via several different routes, including orally,… Read Abstract

• Sharon W T Chew 1 2, Yongpeng Zeng 2, Mingyue Cui 2 3, Hao Chang 2, Mengjia Zheng 2, Shi Wei 4, Wenting Zhao 2, Chenjie Xu 1 2 3. 2019 Apr In Situ Generation of Zinc Oxide Nanobushes on Microneedles as Antibacterial Coating

  This paper introduces a facile and scalable method to generate a layer of antibacterial coating on microneedles. The antibacterial coating (i.e., zinc oxide nanobushes) is generated on the surface of gold-coated polystyrene microneedles using the hydrothermal growth method. The antimicrobial property is examined using the agar diffusion test with both gram-positive and gram-negative bacteria. Read Abstract

• Artif Cells Nanomed Biotechnol. . 2019 Dec Green synthesis of zinc oxide nanoparticles using different plant extracts and their antibacterial activity against Xanthomonas oryzae pv. oryzae

  The synthesis of metal oxide nanoparticles with the use of plant extract is a promising alternative to the conventional chemical method. This work aimed to synthesize zinc oxide nanoparticles (ZnONPs) using plant extract of chamomile flower (Matricaria chamomilla L.), olive leave (Olea europaea) and red tomato fruit (Lycopersicon esculentum M.). The synthesized ZnONPs were characterized… Read Abstract

• Chem Biol Interact.. 2018 Apr Mechanistic study on antibacterial action of zinc oxide nanoparticles synthesized using green route

  A large array of diseases caused by bacterial pathogens and origination of multidrug resistance in their gene provokes the need of developing new vectors or novel drug molecules for effective drug delivery and thus, better treatment of disease. The nanoparticle has emerged as a novel drug molecule in last decade and has been used in… Read Abstract

• Sensors (Basel). . 2017 Jul Zinc Oxide-Based Self-Powered Potentiometric Chemical Sensors for Biomolecules and Metal Ions

  Advances in the miniaturization and portability of the chemical sensing devices have always been hindered by the external power supply problem, which has focused new interest in the fabrication of self-powered sensing devices for disease diagnosis and the monitoring of analytes. This review describes the fabrication of ZnO nanomaterial-based sensors synthesized on different conducting substrates… Read Abstract

• Antonie Van Leeuwenhoek. . 2018 Jun Zinc oxide nanoparticle inhibits the biofilm formation of Streptococcus pneumoniae

  Biofilms are structured consortia of microbial cells that grow on living and non living surfaces and surround themselves with secreted polymers. Infections with bacterial biofilms have emerged as a foremost public health concern because biofilm growing cells can be highly resistant to both antibiotics and host immune defenses. Zinc oxide nanoparticles have been reported as… Read Abstract

• J Trace Elem Med Biol. 2019 Jan Zinc overload mediated by zinc oxide nanoparticles as innovative anti-tumor agent

  The predicted global cancer burden is expected to surpass 20 million new cancer cases by 2025. Despite recent advancement in tumor therapy, a successful cancer treatment remains challenging. The emerging field of nanotechnology offers great opportunities for diagnosis, imaging, as well as treatment of cancer. Zinc oxide nanoparticles (ZnO NP) were shown to exert selective… Read Abstract

• Plant Physiol Biochem.. 2018 Sep Zinc oxide nanoparticles phytotoxicity on halophyte from genus Salicornia

  This study deals with the effect of zinc oxide nanoparticles (ZnO NPs) on halophyte from the genus Salicornia. The presence of ZnO nanoparticles (100 and 1000 mg/L) in the solid culture medium resulted in the negative effects on plant growth in the concentration-dependent manner. The shoot length of plant cultivated with 1000 mg/L ZnO NPs… Read Abstract

• Poultry Science . 2019 Mar Effects of zinc oxide nanoparticles on growth performance and concentrations of malondialdehyde, zinc in tissues, and corticosterone in broiler chickens under heat stress conditions.

  The use of nanominerals, such as nano-zinc, represents a promising and emerging technology in the animal farming industry. Due to the small particle size and bioavailability of nano-zinc, it can be easily assimilated in the digestive system, thereby reducing excretion and environmental pollution. The present study was conducted to assess the effects of zinc oxide… Read Abstract

• Animal Science Journal. 2015 Aug Zinc-bearing zeolite clinoptilolite improves tissue zinc accumulation in laying hens by enhancing zinc transporter gene mRNA abundance.

  A study was conducted to investigate effects of zinc-bearing zeolite clinoptilolite (ZnCP), as an alternative for zinc sulfate (ZnSO4), on laying performance, tissue Zn accumulation and Zn transporter genes expression in laying hens. Hy-Line Brown laying hens were allocated to three treatments, each of which had six replicates with 15 hens per replicate, receiving basal… Read Abstract

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