Potassium Sulfate EP Granular

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• Nanomedicine. 2019 Jan Controlled release of dexamethasone sodium phosphate with biodegradable nanoparticles for preventing experimental corneal neovascularization.

  Corneal neovascularization (CNV) leads to the loss of corneal transparency and vision impairment, and can ultimately cause blindness. Topical corticosteroids are the first line treatment for suppressing CNV, but poor ocular bioavailability and rapid clearance of eye drops makes frequent administration necessary. Patient compliance with frequent eye drop application regimens is poor. We developed biodegradable… Read Abstract

• Nanomedicine. 2019 Apr Receptor for advanced glycation end products: a key molecule in the genesis of chronic kidney disease vascular calcification and a potential modulator of sodium phosphate co-transporter PIT-1 expression.

  BACKGROUND: Chronic kidney disease (CKD) is associated with increased cardiovascular mortality, frequent vascular calcification (VC) and accumulation of uraemic toxins. Advanced glycation end products and S100 proteins interact with the receptor for advanced glycation end products (RAGE). In the present work, we aimed to investigate the role(s) of RAGE in the CKD-VC process. METHODS: Apoe-/- or Apoe-/-Ager… Read Abstract

• Equine Vet J.. 2019 Sep Nebulisation of dexamethasone sodium phosphate for the treatment of severe asthmatic horses.

  BACKGROUND: Inhaled corticosteroids are effective in the treatment of equine asthma. A recent study reported that nebulisation of injectable dexamethasone had low systemic bioavailability in healthy horses and could represent a cost-effective therapy for equine inflammatory lung diseases. OBJECTIVES: To determine the effects of dexamethasone nebulisation on lung function in severe asthmatic horses. It was hypothesised that… Read Abstract

• Am J Vet Res.. 1996 Dec Effect of sodium bisulfate on ammonia concentration, fly population, and manure pH in a horse barn.

  OBJECTIVE: To evaluate the effectiveness of altering the pH of manure with sodium bisulfate, thereby decreasing ammonia concentration and fly population in a horse barn environment. ANIMALS: 4 mixed-breed pony stallions. PROCEDURE: The 4-week study was scheduled with 2 weeks of treatment (with 2 application rates) and 2 weeks with no treatment (control weeks). During treatment weeks,… Read Abstract

• Send to Poult Sci.. 2012 May Effect of dietary adipic acid and corn dried distillers grains with solubles on laying hen performance and nitrogen loss from stored excreta with or without sodium bisulfate.

  Effects of dietary adipic acid (0 vs. 1%) and corn dried distillers grains with solubles (DDGS; 0 vs. 20%) were evaluated on hen performance and egg characteristics from 26 to 34 wk of age. Four isocaloric and isonitrogenous diets were randomly assigned to blocks of 6 consecutive cages (36 cages per diet; 2 hens per… Read Abstract

• Poult Sci.. 2012 Sep The effect of sodium bisulfate on Salmonella viability in broiler litter.

  Controlling Salmonella populations on commercial broiler grow out farms is a crucial step in reducing Salmonella contamination in processing plants. Broiler litter harbors many species of pathogenic bacteria including Salmonella. Sodium bisulfate has been shown to reduce concentration of bacteria in broiler litter. In experiments 1 and 2, sodium bisulfate was applied to broiler litter… Read Abstract

• Send to Eur J Hosp Pharm.. 2015 May Stability of octreotide acetate decreases in a sodium bisulfate concentration-dependent manner: compatibility study with morphine and metoclopramide injections.

  PURPOSE: Sodium bisulfate is known to affect the stability of octreotide. However, the critical concentration of sodium bisulfate is not known. Therefore, we assessed the critical concentration of sodium bisulfate needed to preserve the stability of octreotide using actual drugs containing sodium bisulfate. METHODS: Although morphine and metoclopramide preparations are considered to be compatible with octreotide, some… Read Abstract

• Poult Sci.. 2015 Dec Evaluation of feed grade sodium bisulfate impact on gastrointestinal tract microbiota ecology in broilers via a pyrosequencing platform.

  The gastrointestinal microbial community in broiler chickens consists of many different species of bacteria, and the overall microbiota can vary from bird to bird. To control pathogenic bacteria in broilers and improve gut health, numerous potential dietary amendments have been used. In this study, we used a pyrosequencing platform to evaluate the effect of sodium… Read Abstract

• Mediators Inflamm.. 1970 Jan Andrographolide Sodium Bisulfate Prevents UV-Induced Skin Photoaging through Inhibiting Oxidative Stress and Inflammation.

  Andrographolide sodium bisulfate (ASB), a water-soluble form made from andrographolide through sulfonating reaction, is an antioxidant and anti-inflammatory drug; however, the antiphotoaging effect of ASB has still not been revealed. Oxidative stress and inflammation are known to be responsible for ultraviolet (UV) irradiation induced skin damage and consequently premature aging. In this study, we aimed… Read Abstract

• Chem Pharm Bull (Tokyo).. 2018 Jan Tofogliflozin Salt Cocrystals with Sodium Acetate and Potassium Acetate

  We investigated the salt cocrystals formed by tofogliflozin with sodium acetate and potassium acetate by determining the crystal structures of the salt cocrystals and characterizing the solid states. The salt cocrystal screening using the slurry method and the liquid-assisted grinding method resulted in the formation of tofogliflozin-sodium acetate 1 : 1 and tofogliflozin-potassium acetate 1 : 1 salt cocrystals.… Read Abstract

• Food Chem.. 2018 Aug Nitrite Accumulation Characteristics of Partial Denitrification in Different Sludge Sources Using Sodium Acetate as Carbon Source

  Cytotoxicity and genotoxicity of sodium acetate (SA), sodium diacetate (SDA), and potassium sorbate (PS) was tested on Human Umbilical Vein Endothelial Cells (HUVEC). Cytotoxicity was investigated by MTT assay and flow cytometry analysis, while genotoxicity was evaluated using DNA fragmentation and DAPI staining assays. The growth of treated HUVECs with various concentrations of SA, SDA… Read Abstract

• Semin Nephrol.. 2014 May Role of Circadian Rhythms in Potassium Homeostasis

  It has been known for decades that urinary potassium excretion varies with a circadian pattern. In this review, we consider the historical evidence for this phenomenon and present an overview of recent developments in the field. Extensive evidence from the latter part of the last century clearly demonstrates that circadian potassium excretion does not depend… Read Abstract

• Semin Nephrol.. 2013 May Potassium in hypertension and cardiovascular disease.

  The increased prevalence of hypertension and cardiovascular disease in industrialized societies undoubtedly is associated with the modern high-sodium/low-potassium diet. Extensive experimental and clinical data strongly link potassium intake to cardiovascular outcome. Most studies suggest that the sodium-to-potassium intake ratio is a better predictor of cardiovascular outcome than either nutrient individually. A high-sodium/low-potassium environment results in… Read Abstract

• Phys Chem Chem Phys.. 2018 May Selective sodium intercalation into sodium nickel-manganese sulfate for dual Na-Li-ion batteries.

  Double sodium transition metal sulfates combine in themselves unique intercalation properties with eco-compatible compositions – a specific feature that makes them attractive electrode materials for lithium and sodium ion batteries. Herein, we examine the intercalation properties of novel double sodium nickel-manganese sulfate, Na2Ni1/2Mn1/2(SO4)2, having a large monoclinic unit cell, through electrochemical and ex situ diffraction… Read Abstract

• Phys Chem Chem Phys. 2018 Dec PI3K/Akt signaling pathway and Hsp70 activate in hippocampus of rats with chronic manganese sulfate exposure.

  Manganese (Mn) has come to the forefront of environmental concerns due to its neurotoxicity. However, the toxic effect of Mn is not fully understood. The purpose of this study is to investigate the impacts of chronic manganese sulfate (MnSO4) exposure in regulating the phosphatidylinositol 3 kinase/protein kinase B (PI3K/Akt) signaling pathway in rats. In this… Read Abstract

• Nutrition. 1990 Jul Protein and fat utilization by humans as affected by calcium phosphate, calcium carbonate, and manganese gluconate supplements.

  The object of this study was to determine the effect of calcium carbonate or calcium phosphate supplements on dietary protein and fat utilization from low and high manganese diets. During the 63-day study, the 14 human adult subjects ate a constant laboratory controlled diet. In separate periods, subjects consumed the basal diet alone or with… Read Abstract

• J Hazard Mater. 2019 Mar Mineralization of organics in hazardous waste sulfuric acid by natural manganese oxide ore and a combined MnO2/activated carbon treatment to produce qualified manganese sulfate.

  To effectively dispose and utilize the hazardous waste H2SO4 generated from alkylation, an environmentally friendly and feasible technology for the simultaneous oxidative degradation of organics and consumption of H2SO4 was developed. Pyrolusite, a natural manganese oxide ore, was used for the oxidative degradation and mineralization of the organics, and reduction leaching of Mn from the… Read Abstract

• Genome Res.. 1999 Jun Improved DNA sequencing accuracy and detection of heterozygous alleles using manganese citrate and different fluorescent dye terminators.

  The use of dideoxynucleotide triphosphates labeled with different fluorescent dyes (dye terminators) is the most versatile method for automated DNA sequencing. However, variation in peak heights reduces base-calling accuracy and limits heterozygous allele detection, favoring use of dye-labeled primers for this purpose. We have discovered that the addition of a manganese salt to the PE… Read Abstract

• Osteoarthritis Cartilage.. 2001 Jan Effects of an orally administered mixture of chondroitin sulfate, glucosamine hydrochloride and manganese ascorbate on synovial fluid chondroitin sulfate 3B3 and 7D4 epitope in a canine cruciate ligament transection model of osteoarthritis.

  OBJECTIVE: To evaluate effects of an orally administered mixture of chondroitin sulfate, glucosamine hydrochloride and manganese ascorbate (CS-G-M) on articular cartilage metabolism in dogs with cranial cruciate ligament (CCL) deficient and reconstructed knees, as reflected by concentrations of synovial fluid 3B3, 7D4 and total sulfated glycosaminoglycan (GAG). METHODS: Sixteen adult dogs that underwent unilateral CCL transection… Read Abstract

• Mil Med. . 1999 Feb Glucosamine, chondroitin, and manganese ascorbate for degenerative joint disease of the knee or low back: a randomized, double-blind, placebo-controlled pilot study.

  OBJECTIVE: A 16-week randomized, double-blind, placebo-controlled crossover trial of a combination of glucosamine HCl (1,500 mg/day), chondroitin sulfate (1,200 mg/day), and manganese ascorbate (228 mg/day) in degenerative joint disease (DJD) of the knee or low back was conducted. METHODS: Thirty-four males from the U.S. Navy diving and special warfare community with chronic pain and radiographic DJD of… Read Abstract

• Osteoarthritis Cartilage.. 2000 Sep Efficacy of a combination of FCHG49 glucosamine hydrochloride, TRH122 low molecular weight sodium chondroitin sulfate and manganese ascorbate in the management of knee osteoarthritis.

  OBJECTIVES: The objective of this study was to evaluate the oral combination of glucosamine HCl, sodium chondroitin sulfate and manganese ascorbate for the treatment of osteoarthritis (OA) of the knee. DESIGN: A randomized placebo-controlled study design was implemented. We recruited 93 patients with OA of the knee from a single center. The intervention group received 1000 mg… Read Abstract

• Exp Biol Med (Maywood). 2001 Feb Effect of pre-loading oral glucosamine HCl/chondroitin sulfate/manganese ascorbate combination on experimental arthritis in rats.

  The therapeutic effect of a nutritional supplement consisting of a combination of glucosamine hydrochloride (FCHG49), purified sodium chondroitin sulfate (TRH122), and manganese ascorbate (GCM)3 was investigated in the rat model of collagen-induced autoimmune arthritis (CIA). The GCM compound was mixed with a palatable nutritional paste (Nutri-cal [NC]). Oral administration of the NC/GCM compound was initiated… Read Abstract

• Biol Trace Elem Res. 2019 Dec Dose-Dependent Absorption Profile of Different Magnesium Compounds.

  Magnesium, one of the basic elements for the human body, is necessary for many physiological functions. Magnesium deficiency is widely observed as a result of the reduced nutrient content of foods, over-cooking, diseases, drugs, alcohol, and caffeine consumption. Taking a dietary supplement is necessary magnesium deficiency. It has been demonstrated that absorption of organic magnesium… Read Abstract

• Biol Trace Elem Res. 2019 Jan Timeline (Bioavailability) of Magnesium Malate and other Compounds in Hours: Which Magnesium Compound Works Best?

  Magnesium is an element of great importance functioning because of its association with many cellular physiological functions. The magnesium content of foods is gradually decreasing due to food processing, and magnesium supplementation for healthy living has become increasingly popular. However, data is very limited on the bioavailability of various magnesium preparations. The aim of this… Read Abstract

• J Pharm Biomed Anal. 2015 Jan Evaluation of enantiomeric purity of magnesium-L-aspartate dihydrate.

  Magnesium supplementation in form of organic magnesium salts is a very popular practice. We examined the enantiomeric purity of “Magnesium aspartate dihydrate” monographed in the European Pharmacopeia. A chiral capillary zone electrophoresis using (2-hydroxypropyl)-β-cyclodextrin coupled to laser induced fluorescence detection and a HPLC-fluorescence method with chiral derivatization using o-phthaldialdehyde and N-acetyl-L-cysteine as an orthogonal method… Read Abstract

• Dalton Trans. 2019 May Lipid-Coated, pH-Sensitive Magnesium Phosphate Particles for Intracellular Protein Delivery.

  PURPOSE: To develop cationic lipid-coated magnesium phosphate nanoparticles (LPP) for intracellular catalase (CAT) delivery. METHODS: Magnesium phosphate nanoparticles (MgP NP) were prepared by micro-emulsion precipitation and mixed with catalase-loaded cationic liposomes (DOTAP/cholesterol) to yield LPP formulation of catalase (LPP-CAT). The size and ζ-potential of LPP-CAT were measured by dynamic light scattering. The pH-sensitivity of LPP-CAT was determined… Read Abstract

• J Biomed Mater Res B Appl Biomater. 2019 Jul Silver (Ag) doped magnesium phosphate microplatelets as next-generation antibacterial orthopedic biomaterials.

  This article reports for the first time our successful result in the synthesis of antibacterial single-phase newberyite (NB, MgHPO4 .3H2 O), an important magnesium phosphate (MgP) bioceramic. The prime novelty lies in the fact that we explore novel MgPs as next-generation orthopedic biomaterials as opposed to conventional calcium phosphates (CaP). While NB has already shown… Read Abstract

• Ying Yong Sheng Tai Xue Bao. 2019 Sep Improvement effects of quicklime and calcium magnesium phosphate fertilizer on acidified soil cultivating Codonopsis tangshen.

  To solve the problem of soil acidification in the cultivation of Codonopsis tangshen, laboratory experiments were carried out to investigate C. tangshen seed germination, seedling growth and soil exchangeable acid, microbial community structure after applying quicklime (QL) and calcium magnesium phosphate fertilizer (CMP). The results showed that QL and CMP treatments significantly improved the survival… Read Abstract

• Appl Microbiol Biotechnol. 2017 Oct Biosynthesis of copper carbonate nanoparticles by ureolytic fungi

  In this research, the ureolytic fungi Neurospora crassa, Pestalotiopsis sp. and Myrothecium gramineum were investigated for the preparation of nanoscale copper carbonate and the role of fungal extracellular protein in such mineral formation. After incubation in urea-modified media, carbonate-laden fungal supernatants were used for the precipitation of copper carbonate, with experimental results agreeing closely with… Read Abstract

• Int Dent J. . 2005 Oct Calcium hydroxide: a review.

  Calcium hydroxide is a multipurpose agent, and there have been an increasing number of indications for its use. Some of its indications include direct and indirect pulp capping, apexogenesis, apexification, treatment of; root resorption, iatrogenic root perforations, root fractures, replanted teeth and interappointment intracanal dressing. The purpose of this paper is to review the properties… Read Abstract

• Nanoscale. 2019 Apr A template-free and low temperature method for the synthesis of mesoporous magnesium phosphate with uniform pore structure and high surface area.

  Mesoporous phosphates are a group of nanostructured materials with promising applications, particularly in biomedicine and catalysis. However, their controlled synthesis via conventional template-based routes presents a number of challenges and limitations. Here, we show how to synthesize a mesoporous magnesium phosphate with a high surface area and a well-defined pore structure through thermal decomposition of… Read Abstract

• Int Endod J. 1991 May The antimicrobial effect of calcium hydroxide as a short-term intracanal dressing.

  The antibacterial effect of calcium hydroxide as a short-term intracanal dressing was clinically evaluated by applying the medicament for 10 minutes or 7 days in root canals of teeth with periapical lesions. The results showed that the 7-day dressing efficiently eliminated bacteria which survived biomechanical instrumentation of the canal, while the 10-minute application was ineffective. Read Abstract

• Compend Contin Educ Dent. 1970 Jan Calcium hydroxide-based root canal sealers: an updated literature review.

  Important role in sealing the root canal system with the entombment of remaining microorganisms and filling inaccessible areas of prepared canals. This article reviews sealing ability, biocompatibility, antibacterial activity, solubility, and toxicity of calcium hydroxide based root canal sealers. Read Abstract

• Appl Microbiol Biotechnol. 2011 Mar Effects of nitrogen catabolite repression and di-ammonium phosphate addition during wine fermentation by a commercial strain of S. cerevisiae.

  Two deletion mutants expected to be defective in nitrogen catabolite repression (NCR) were constructed in a commercial wine yeast background M2: a ure2 mutant and a dal80 gzf3 double mutant. Wild-type and both mutant strains were fermented in Sauvignon Blanc grape juice with and without addition of di-ammonium phosphate (DAP). The dal80 gzf3 double mutant… Read Abstract

• J. Serb. Chem. Soc.. 2010 Jan Synthesis and characterization of ammonium phosphate fertilizers with boron

  The concentration of boron, an essential micronutrient for plants, presents a narrow range between deficiency and toxicity. In order to provide the boron requirement for plants, and to avoid toxicity problems, boron compounds are mixed with basic fertilizers. Sodium borate pentahydrate was used as a boron source. Ammonium orthophosphates fertilizers with boron were prepared by… Read Abstract

• Revista Brasileira de Ciência do Solo. 2018 Dec Acid Ammonium Citrate as P Extractor for Fertilizers of Varying Solubility

  There are several globally accepted methods to chemically characterize P-fertilizers, but not all are suitable to predict the agronomic efficiency of the P sources in terms of plant nutrition. Our aim was to investigate the performance of P extractors for fertilizers, investigating the consistency of different methods for P sources of varying properties and the… Read Abstract

• Journal of Experimental Botany. 2017 Mar Ammonium as a signal for physiological and morphological responses in plants

  Ammonium is a major inorganic nitrogen source for plants. At low external supplies, ammonium promotes plant growth, while at high external supplies it causes toxicity. Ammonium triggers rapid changes in cytosolic pH, in gene expression, and in post-translational modifications of proteins, leading to apoplastic acidification, co-ordinated ammonium uptake, enhanced ammonium assimilation, altered oxidative and phytohormonal… Read Abstract

• Sheng Wu Gong Cheng Xue Bao. 2019 Sep Acellular vascular scaffolds modified by ammonium phosphate zwitterions can effectively resist thrombosis and promote endothelialization in vitro.

  Due to limited availability of autologous blood vessels (blood vessels from the same recipient used for vascular transplantation materials) and inadequate growth ability of non-autologous blood vessels (artificial blood vessel transplantation materials), more and more attention has been paid to tissue engineering blood vessels. In this study, we constructed an ammonium phosphate zwitterion modified acellular… Read Abstract

• Calcified Tissue International. 2001 Sep Mechanisms of action and therapeutic potential of strontium in bone.

  The processes of bone resorption and formation are tightly governed by a variety of systemic and local regulatory agents. In addition, minerals and trace elements affect bone formation and resorption through direct or indirect effects on bone cells or bone mineral. Some trace elements closely chemically related to calcium, such as strontium (Sr), have pharmacological… Read Abstract

• Journal of Biomedical Materials Research Part A. 2015 Oct Strontium-impregnated bioabsorbable composite for osteoporotic fracture fixation.

  Osteoporosis impairs the bone-healing process as well as bone fracture fixation. The intervention of osteoporosis is considered to be one part of bone fracture treatment. Thus, orthopedic fixators impregnated with antiosteoporosis regimens will improve fracture fixation in osteoporotic bone. In this study, the strontium (Sr) and calcium phosphate ceramic (CPC) were mixed first and then… Read Abstract

• Food Chemistry. 2014 Jan Geographic determination of coffee beans using multi-element analysis and isotope ratios of boron and strontium.

  This study aims to evaluate the feasibility of using chemical and isotopic compositions of coffee beans to identify their geographic origins. Twenty-one Coffea arabica beans collected from 14 countries in 3 major coffee-producing regions, Africa, America and Asia, were analysed for multi-element of B, Rb, Sr, Ba, Fe, Mn and Zn, as well as isotopic… Read Abstract

• Poultry Science . 2019 Mar Effects of zinc oxide nanoparticles on growth performance and concentrations of malondialdehyde, zinc in tissues, and corticosterone in broiler chickens under heat stress conditions.

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• The Journal of Clinical Dentistry. 2014 Jan The effect of zinc lactate and magnolia bark extract added tablets on volatile sulfur-containing compounds in the oral cavity.

  A controlled, clinical, double-blind study was conducted to assess the efficacy of sugar-free tablets containing zinc lactate and magnolia bark extract (MBE) on oral volatile sulfur-containing compounds (VSC) versus placebo tablets for two hours. METHODS: In order to join the study, subjects had to have at least 24 teeth, no report of oral and systemic… Read Abstract

• Animal Science Journal. 2015 Aug Zinc-bearing zeolite clinoptilolite improves tissue zinc accumulation in laying hens by enhancing zinc transporter gene mRNA abundance.

  A study was conducted to investigate effects of zinc-bearing zeolite clinoptilolite (ZnCP), as an alternative for zinc sulfate (ZnSO4), on laying performance, tissue Zn accumulation and Zn transporter genes expression in laying hens. Hy-Line Brown laying hens were allocated to three treatments, each of which had six replicates with 15 hens per replicate, receiving basal… Read Abstract

• Oral Health and Preventive Dentistry. 2010 Jan The effects of a zinc citrate dentifrice on bacteria found on oral surfaces.

  PURPOSE: Clinical studies with dentifrices formulated with antimicrobial ingredients typically examine the effects of their use on clinical parameters of dental plaque and gingivitis. The effects of routine use of these formulations on the microorganisms found in the distinct regions of the human mouth remain unexplored. The present cross-over design clinical study compared the effects… Read Abstract

• Korean Journal of Urology. 2012 Feb Induction of apoptosis of bladder cancer cells by zinc-citrate compound.

  PURPOSE: Zinc is one of the trace minerals in the body and is known to have an anticancer effect by inducing apoptosis in prostate cancer. We aimed to investigate the antiproliferative effects of a zinc-citrate compound in bladder cancer. MATERIALS AND METHODS: A bladder cancer cell line (MBT-2) was treated with a zinc-citrate compound at… Read Abstract

• The Journal of Nutrition. 2014 Feb Zinc absorption by young adults from supplemental zinc citrate is comparable with that from zinc gluconate and higher than from zinc oxide.

  The water-soluble zinc salts gluconate, sulfate, and acetate are commonly used as supplements in tablet or syrup form to prevent zinc deficiency and to treat diarrhea in children in combination with oral rehydration. Zinc citrate is an alternative compound with high zinc content, slightly soluble in water, which has better sensory properties in syrups but… Read Abstract

• Food and Chemical Toxicology. 2019 Mar Zinc citrate incorporation with whey protein nanoparticles alleviate the oxidative stress complication and modulate gene expression in the liver of rats.

  This study aimed to evaluate the hepatoprotective effect of whey protein nanoparticles (WP-NPs) coated Zinc citrate (Zn) against oxidative stress complications and disturbances in gene expression in rats treated with CCl4. WP-NPs were used to coat Zn at three levels and amino acids content was determined in WP-NPs and the fabrications. Seven groups of male… Read Abstract

• Journal of Veterinary Dentistry. 2001 Dec Clinical and microbiological effects of oral zinc ascorbate gel in cats.

  The clinical and microbiological effects of zinc ascorbate gel applied orally in cats were evaluated during a 42-day study period. Cats were divided randomly into two equal groups, with the treatment group (18 cats) receiving zinc ascorbate gel and the control group (18 cats) receiving a placebo (0.9% sterile saline). Clinical parameters evaluated biweekly included… Read Abstract

• Clinical, Cosmetic and Investigational Dermatology. 2011 Oct Susceptibility of Propionibacterium acnes isolated from patients with acne vulgaris to zinc ascorbate and antibiotics.

  PURPOSE: The in vitro antimicrobial activity of ascorbic acid derivatives against Propionibacterium acnes was tested either alone or in combination with a variety of antimicrobial agents, and their fractional inhibitory concentration index was determined using checkerboard tests. The antimicrobial effectiveness of zinc ascorbate in the treatment of acne vulgaris, either alone or in combination with… Read Abstract

• Clinical, Cosmetic and Investigational Dermatology. 2012 Sep Zinc ascorbate has superoxide dismutase-like activity and in vitro antimicrobial activity against Staphylococcus aureus and Escherichia coli.

  BACKGROUND: Acne vulgaris is a common dermatological disease, and its pathogenesis is multifactorial. OBJECTIVE: We examined whether the ascorbic acid derivative zinc ascorbate has superoxide dismutase (SOD)-like activity. SOD is an enzyme that controls reactive oxygen species production. In addition, the in vitro antimicrobial activity of zinc ascorbate against the Gram-positive bacterium Staphylococcus aureus and… Read Abstract

• Contact Dermatitis. 2000 Feb Strontium nitrate suppresses chemically-induced sensory irritation in humans.

  Skin care products are complex formulations that may cause sensory irritation symptoms, characterized by stinging, burning, and itching. Substances capable of counteracting sensory irritation are of great practical interest. Strontium salts have been demonstrated to inhibit sensory irritation and inflammation when applied topically. In this double-blind study, we evaluated the efficacy of strontium nitrate in… Read Abstract

• Dermatology. 2010 May Strontium nitrate decreased histamine-induced itch magnitude and duration in man.

  BACKGROUND: Previous studies have demonstrated that strontium salts have a potent and broad ability to suppress sensory irritation. OBJECTIVE: To ascertain the possible antipruritic effects of topical strontium salts, we conducted a double-blind randomized study to evaluate the effect of 20% strontium nitrate on itch magnitude (intensity) and duration. METHODS: In 8 human subjects, strontium… Read Abstract

• The American Journal of Clinical Nutrition. 2016 Aug Bioavailability of potassium from potatoes and potassium gluconate: a randomized dose response trial.

  BACKGROUND: The bioavailability of potassium should be considered in setting requirements, but to our knowledge, the bioavailability from individual foods has not been determined. Potatoes provide 19-20% of potassium in the American diet.OBJECTIVE: We compared the bioavailability and dose response of potassium from nonfried white potatoes with skin [targeted at 20, 40, and 60 milliequivalents… Read Abstract

• British Journal of Anaesthesia. 2013 May Effect of intrathecal magnesium in the presence or absence of local anaesthetic with and without lipophilic opioids: a systematic review and meta-analysis.

  Spinal anaesthesia is the primary anaesthetic technique for many types of surgery. Adjuncts to the local anaesthetics (LA) used in spinal anaesthesia can exhibit undesirable side-effects, limiting their use, but magnesium may have advantages in this respect. We sought randomized control trials (RCTs) in patients undergoing all types of surgery and in women in labour… Read Abstract

• Acta Neurologica Belgica. 2019 Feb The efficacy of magnesium oxide and sodium valproate in prevention of migraine headache: a randomized, controlled, double-blind, crossover study.

  Migraine is a disabling disorder that affects the quality of life of patients. Different medications have been used in prevention of migraine headache. In this study, we evaluated the effectiveness of magnesium oxide in comparison with valproate sodium in preventing migraine headache attacks. This is a single-center, randomized, controlled, crossover trial which is double-blind, 24-week,… Read Abstract

• Acta Universitatis Palackianae Olomucensis. 1991 Jan Osteoporosis treated with magnesium lactate.

  33 patients with senile, 18 patients with postmenopausal and 9 patients with medicamentous (corticosteroids) osteoporosis were treated with single therapy of Mg lactate (37 patients) and with the combined one of Mg lactate and Na fluoride (23 patients). They were evaluated in three periods of half a year, one year, two years. The better results… Read Abstract

• Nephrology Dialysis Transplantation. 2017 Mar Magnesium lactate in the treatment of Gitelman syndrome: patient-reported outcomes.

  BACKGROUND: Gitelman syndrome (GS) is a rare recessively inherited renal tubulopathy associated with renal potassium (K) and magnesium (Mg) loss. It requires lifelong K and Mg supplementation at high doses that are at best unpalatable and at worst, intolerable. In particular, gastrointestinal side effects often limit full therapeutic usage. METHODS: We report here the analysis… Read Abstract

• Drug Development and Industrial Pharmacy. 2018 Sep The absolute bioavailability and the effect of food on a new magnesium lactate dihydrate extended-release caplet in healthy subjects.

  OBJECTIVE: To assess the absolute bioavailability of 20 mEq magnesium lactate extended-release (ER) caplets and to assess the effect of food on the pharmacokinetics of these ER caplets. SIGNIFICANCE: Magnesium in different salt forms is available as over-the-counter oral formulations. The absorption and bioavailability is highly affected by the water solubility of the salt form.… Read Abstract

• Acta scientiarum polonorum. Technologia alimentaria.. 2018 Jul Quality of yogurt fortified with magnesium lactate.

  During the tests carried out with rats the organic complex magnesium gluconate was examined for its bioavailability and its stress-reducing properties after oral application. The increase of magnesium concentration in serum achieved by means of magnesium gluconate turned out to be higher than the increase of concentration due to the administration of magnesium chloride. Just… Read Abstract

• Zhonghua fu chan ke za zhi. 1997 Oct Oral low-dose magnesium gluconate preventing pregnancy induced hypertension.

  OBJECTIVE: To study the effects of oral low-dose magnesium gluconate in prevention of pregnancy induced hypertension (PIH) and its mechanism. METHODS: A prospective randomized double-blind study was carried out in 51 pregnant women as treatment group (including 22 cases as treatment group 1 and 29 cases as treatment group 2) and 51 pregnant women as… Read Abstract

• Journal of Cardiovascular Pharmacology. 2018 Dec Magnesium Citrate Protects Against Vascular Calcification in an Adenine-induced Chronic Renal Failure Rat Model.

  BACKGROUND: Hypomagnesemia was identified as a strong risk factor for cardiovascular disease in patients with chronic renal failure (CRF). However, the effects of magnesium (Mg) on vascular calcification (VC) have not been fully elucidated. Thus, we aim to determine the effects of Mg citrate (MgCit) on VC in CRF rats. METHODS: Rats were divided into… Read Abstract

• Journal of Cutaneous Medicine and Surgery. 2018 May A Case of Hailey-Hailey Disease Managed With Oral Magnesium Citrate and High-Dose Vitamin D3.

  Hailey-Hailey disease, or benign familial pemphigus, is a rare blistering disease originally described in 1939. The disease is due to an autosomal dominant mutation in the ATP2C1 gene on chromosome 3, which encodes for an adenosine triphosphate-dependent calcium pump in the Golgi apparatus whose function is to maintain intercellular calcium homeostasis. Common treatments for Hailey-Hailey… Read Abstract

• Journal of Nephrology. 2019 Feb Control of metabolic predisposition to cardiovascular complications of chronic kidney disease by effervescent calcium magnesium citrate: a feasibility study.

  AIMS: Cardiovascular (CV) complications are common in chronic kidney disease (CKD). Numerous metabolic disturbances including hyperphosphatemia, high circulating calciprotein particles (CPP), hyperparathyroidism, metabolic acidosis, and magnesium deficiency are associated with, and likely pathogenic for CV complications in CKD. The goal of this feasibility study was to determine whether effervescent calcium magnesium citrate (EffCaMgCit) ameliorates the… Read Abstract

• Current Opinion in Clinical Nutrition & Metabolic Care. 2014 May Meeting iron needs for infants and children

  Iron deficiency early in life is associated with impaired neurological development. This study reviews the latest research on how to best meet iron requirements in infants and children. There is concurrent evidence that delayed cord clamping is well tolerated and improves infant iron stores. Iron supplements or enriched complementary foods starting before 6 months of… Read Abstract

• Vojnosanit Pregl. 2006 Feb Resorption and tolerance of the high doses of ferrous sulfate and ferrous gluconate in the patients on peritoneal dialysis.

  BACKGROUND/AIM: Iron supplementation plays a crucial role in peritoneal dialysis (PD) patients. Oral iron substitution is more convenient than intravenous therapy in PD patients, but impaired absorption and adverse effects may be limiting factors for oral treatment. The aim of this study was to compare the absorption and side effects of high doses ferrous sulphate… Read Abstract

• Journal of Nutritional Science and Vitaminology. 1991 Apr Improvement in iron deficiency anemia through therapy with ferric ammonium citrate and vitamin C and the effects of aerobic exercise.

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• Cell Discovery. 2018 Mar Antiviral effects of ferric ammonium citrate.

  Iron is an essential nutrient for cell survival and is crucial for DNA replication, mitochondrial function and erythropoiesis. However, the immunological role of iron in viral infections has not been well defined. Here we found the iron salt ferric ammonium citrate (FAC) inhibited Influenza A virus, HIV virus, Zika virus, and Enterovirus 71 (EV71) infections.… Read Abstract

• Send to Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2007 Apr Oral ferric ammonium citrate solution in MRCP for diagnosing low-level obstructive jaundice.

  OBJECTIVE: To evaluate the value of oral ferric ammonium citrate solution as a gastrointestinal contrast agent in diagnosing low-level obstructive jaundice. METHODS: Thirty-six patients who were suspected of low-level obstructive jaundice were performed with magnetic resonance cholangiopancreatography (MRCP) and conventional MRI before and after the administration of oral ferric ammonium citrate solution. The diagnostic accuracy… Read Abstract

• Acta Radiologica. 1999 Jul Ferric ammonium citrate as a positive bowel contrast agent for MR imaging of the upper abdomen. Safety and diagnostic efficacy.

  PURPOSE: To evaluate the safety and diagnostic efficacy of two different doses of ferric ammonium citrate as a paramagnetic oral contrast agent for MR imaging of the upper abdomen. MATERIAL AND METHODS: Ninety-nine adult patients referred for MR imaging for a known or suspected upper abdominal pathology were included in this randomized multicenter double-blind clinical… Read Abstract

• Frontiers in Bioscience. 2004 Sep Copper storage diseases: Menkes, Wilsons, and cancer

  The trace element copper is vital to the healthy functioning of organisms. Copper is used in a multitude of cellular activities including respiration, angiogenesis, and immune responses. Like other metals, copper homeostasis is a tightly regulated process. Copper is transported from dietary intake through the serum and into cells via a variety of transporters. There… Read Abstract

• Survey of Ophthalmology. 2013 Nov Iron, zinc, and copper in retinal physiology and disease.

  The essential trace metals iron, zinc, and copper play important roles both in retinal physiology and disease. They are involved in various retinal functions such as phototransduction, the visual cycle, and the process of neurotransmission, being tightly bound to proteins and other molecules to regulate their structure and/or function or as unbound free metal ions.… Read Abstract

• Nature. 2014 May Copper is required for oncogenic BRAF signalling and tumorigenesis.

  The BRAF kinase is mutated, typically Val 600→Glu (V600E), to induce an active oncogenic state in a large fraction of melanomas, thyroid cancers, hairy cell leukaemias and, to a smaller extent, a wide spectrum of other cancers. BRAF(V600E) phosphorylates and activates the MEK1 and MEK2 kinases, which in turn phosphorylate and activate the ERK1 and… Read Abstract

• Oncotarget. 2016 Jun Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution.

  Copper-ionophores that elevate intracellular bioavailable copper display significant therapeutic utility against prostate cancer cells in vitro and in TRAMP (Transgenic Adenocarcinoma of Mouse Prostate) mice. However, the pharmacological basis for their anticancer activity remains unclear, despite impending clinical trails. Herein we show that intracellular copper levels in prostate cancer, evaluated in vitro and across disease… Read Abstract

• Waste Management & Research. 2017 Jun Optimisation of chemical oxygen demand removal from landfill leachate by sonocatalytic degradation in the presence of cupric oxide nanoparticles.

  Leachate is the liquid formed when waste breaks down in the landfill and water filters through that waste. This liquid is very toxic and can pollute the land, ground water, and water resources. In most countries, it is mandatory for landfills to be protected against leachate. In addition to all other harms to the environment,… Read Abstract

• Biosensors and Bioelectronics. 2018 Feb Efficient label-free chemiluminescent immunosensor based on dual functional cupric oxide nanorods as peroxidase mimics.

  Dual-functional cupric oxide nanorods (CuONRs) as peroxidase mimics are proposed for the development of a flow-through, label-free chemiluminescent (CL) immunosensor. Forming the basis of this cost-efficient, label-free immunoassay, CuONRs, synthesized using a simple hydrothermal method, were deposited onto epoxy-activated standard glass slides, followed by immobilization of biotinylated capture antibodies through a streptavidin bridge. The CuONRs… Read Abstract

• Scientific Reports. 2019 Feb Electromagnon excitation in cupric oxide measured by Fabry-Pérot enhanced terahertz Mueller matrix ellipsometry.

  Here we present the use of Fabry-Pérot enhanced terahertz (THz) Mueller matrix ellipsometry to measure an electromagnon excitation in monoclinic cupric oxide (CuO). As a magnetically induced ferroelectric multiferroic, CuO exhibits coupling between electric and magnetic order. This gives rise to special quasiparticle excitations at THz frequencies called electromagnons. In order to measure the electromagnons… Read Abstract

• International Journal of Pharmaceutics. 2007 Jun Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes.

  A novel method for encapsulating irinotecan into liposomes containing copper gluconate buffered to pH 7.0 with triethanolamine (TEA) has recently been developed. In the present study, the mechanism dictating drug encapsulation and retention inside those liposomes was investigated. Spectroscopic analyses revealed that irinotecan interacted with copper gluconate/TEA in solution. Fourier transformed infrared (FT-IR) spectroscopy indicated… Read Abstract

• Bioresource Technology. 2010 Feb Adsorption of copper-citrate complexes on chitosan: equilibrium modeling.

  The effects of complexes on the adsorption of copper from citrate solutions using chitosan were investigated. Various copper to citrate ratios and solution pHs were used to determine the copper adsorption capacity on the chitosan and a mathematical model was developed to simulate the copper adsorption process. According to the model, the three parameters influencing… Read Abstract

• Pnas. 2014 Jul Excited-state structural dynamics of a dual-emission calmodulin-green fluorescent protein sensor for calcium ion imaging

  Fluorescent proteins (FPs) have played a pivotal role in bioimaging and advancing biomedicine. The versatile fluorescence from engineered, genetically encodable FP variants greatly enhances cellular imaging capabilities, which are dictated by excited-state structural dynamics of the embedded chromophore inside the protein pocket. Visualization of the molecular choreography of the photoexcited chromophore requires a spectroscopic technique… Read Abstract

• Nutrition Reviews. 2012 Jul Role of calcium during pregnancy: maternal and fetal needs

  Although the demand for additional calcium during pregnancy is recognized, the dietary reference intake for calcium was lowered for pregnant women in 1997 to amounts recommended for nonpregnant women (1,000 mg/day), and recently (November 2010) the Institute of Medicine report upheld the 1997 recommendation. It has been frequently reported that women of childbearing age do… Read Abstract

• Journal of Internal Medicine. 2006 May Calcium and vitamin D in the prevention and treatment of osteoporosis – a clinical update

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• Journal of Biological Chemistry. 2014 Apr The plasma membrane calcium pump: new ways to look at an old enzyme.

  The three-dimensional structure of the PMCA pump has not been solved, but its basic mechanistic properties are known to repeat those of the other Ca(2+) pumps. However, the pump also has unique properties. They concern essentially its numerous regulatory mechanisms, the most important of which is the autoinhibition by its C-terminal tail. Other regulatory mechanisms… Read Abstract

• Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2019 Mar Traditional materials from new sources - conflicts in analytical methods for calcium carbonate.

  Calcium carbonate (E170) is a common food and pharmaceutical additive/ingredient. In addition to a source of calcium, the carbonate has uses including as a colour, acidity regulator and bulking agent. Globally, a range of regulatory agencies and pharmacopoeia control the analyses and specification of additives in food, supplements, pharmaceutical substances and excipients. Accordingly, a range… Read Abstract

• Bioresource Technology. 2013 Sep High-level production of calcium malate from glucose by Penicillium sclerotiorum K302.

  In this study, after screening of 9 fungal strains for their ability to produce calcium malate, it was found that Penicillium sclerotiorum K302 among them could produce high-level of calcium malate. Under the optimal conditions, the titer of calcium malate in the supernatant was 88.6 g/l at flask level. During 10-l fermentation, the titer of… Read Abstract

• Journal of Dairy Science. 2019 Jan Calcium lactate as an attractive compound to partly replace salt in blue-veined cheese.

  In addition to their high sodium content, cheeses are thought to induce an acid load to the body, which is associated with deleterious effects on consumers’ health. Our objective was to explore the use of alkalinizing salts in partial substitution of NaCl to reduce both the sodium content and the acid-forming potential of cheese, without… Read Abstract

• Environmental Toxicology and Pharmacology. 2015 Jan Anti-inflammatory effects of calcium citrate in RAW 264.7cells via suppression of NF-κB activation.

  Here we aimed to investigate the anti-inflammatory effects of calcium citrate in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. The anti-inflammatory effects of calcium citrate were investigated by assessing pro-inflammatory factors (NO, ROS, NF-κB, iNOS, and COX-2) and pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α). Treatment of cells with calcium citrate (10-100μM) significantly reduced the generation of intracellular… Read Abstract

• Bioengineered. 2016 Sep Preparation and properties of calcium citrate nanosheets for bone graft substitute.

  A convenient and effective soft chemical method is presented for the synthesis of nano-scaled calcium citrate sheets. The preparation involved the precipitation of nano-calcium citrate by adding ethanol to reach the super saturation state of a solution containing calcium and citrate salts. The obtained nano-calcium citrate formed nanosheets, with the following dimensions: width of about… Read Abstract

• Journal of Food and Drug Analysis. 2018 Jan Codissolution of calcium hydrogenphosphate and sodium hydrogencitrate in water. Spontaneous supersaturation of calcium citrate increasing calcium bioavailability.

  The sparingly soluble calcium hydrogenphosphate dihydrate, co-dissolving in water during dissolution of freely soluble sodium hydrogencitrate sesquihydrate as caused by proton transfer from hydrogencitrate to hydrogenphosphate, was found to form homogenous solutions supersaturated by a factor up to 8 in calcium citrate tetrahydrate. A critical hydrogencitrate concentration for formation of homogeneous solutions was found to… Read Abstract

• Food Research International. 2018 May Supersaturation of calcium citrate as a mechanism behind enhanced availability of calcium phosphates by presence of citrate.

  Dissolution of amorphous calcium phosphate (ACP) in aqueous citrate at varying pH has been studied with perspective of increasing availability of calcium from sidestreams of whey protein, lactose and/or cheese production or on development of new functional foods. ACP formed as an initial precipitate in 0.10 mol L-1 equimolar aqueous calcium chloride, sodium citrate, and sodium hydrogenphosphate… Read Abstract

• Nutrients. 2018 Nov Chronic Ingestion of Sodium and Potassium Bicarbonate, with Potassium, Magnesium and Calcium Citrate Improves Anaerobic Performance in Elite Soccer Players.

  Anaerobic power and anaerobic capacity significantly influence performance in many sport disciplines. These include prolonged sprints in athletics, swimming, or cycling, and other high intensity intermittent sports, such as soccer or basketball. Considering the association of exercise-induced acidosis and fatigue, the ingestion of potential buffering agents such as sodium bicarbonate, has been suggested to attenuate… Read Abstract

• Food Research International. 2019 Feb Calcium citrate insolubilization drives the fouling of falling film evaporators during the concentration of hydrochloric acid whey.

  When dairy powders are produced, the mineral fraction undergoes strong modifications during the vacuum concentration step, leading to the fouling of falling film evaporators. The objective of this study was to determine the nature of the deposits formed during the vacuum concentration of two fouling and highly mineralized products: hydrochloric acid whey and lactic acid… Read Abstract

• Applied and Environmental Microbiology. 1990 Dec Mechanism by which ammonium bicarbonate and ammonium sulfate inhibit mycotoxigenic fungi.

  In this study we examined the mechanism by which ammonium bicarbonate inhibits mycotoxigenic fungi. Elevated extracellular pH, alone, was not responsible for the antifungal activity. Although conidia of Penicillium griseofulvum and Fusarium graminearum had internal pH (pHi) values as high as 8.0 in buffer at an external pH (pHo) of 9.5, their viability was not… Read Abstract

• Chemosphere. 2015 Sep Combination of powdered activated carbon and powdered zeolite for enhancing ammonium removal in micro-polluted raw water.

  Even zeolite is promising in ammonia pollution disposing, its removal efficiency is frequently interfered by organics. As activated carbon has good removal efficiency on organic contaminants, combination of two adsorbents may allow their respective adsorption characteristics into full play. This paper provides a performance assessment of the combination for enhancing ammonium removal in micro-polluted raw… Read Abstract

• Journal of Pharmaceutical Sciences. 2014 Aug Physical characterisation and long-term stability studies on quaternary ammonium palmitoyl glycol chitosan (GCPQ)--a new drug delivery polymer.

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• Acta Physiologica. 2015 Jun Ammonium increases Ca(2+) signalling and upregulates expression of Cav1.2 gene in astrocytes in primary cultures and in the in vivo brain.

  AIM: The primary aim of this study was to identify the effects of hyperammonaemia on functional expression of Cav1.2 L-type Ca(2+) channels in astroglia.METHODS: Primary cultures of mouse astrocytes were used to study effects of chronic treatment (1-5 days) with ammonium chloride, at 1, 3 and 5 mm on depolarization-induced increases in free cytosolic Ca(2+)… Read Abstract

• Journal of Chromatography A. 2016 Dec Headspace gas chromatography based methodology for the analysis of aromatic substituted quaternary ammonium salts.

  The analysis of quaternary ammonium salts (QAS) using GC is often performed by “in injector” pyrolysis to create volatile degradation products for quantification purposes. Besides the risk of severe system contamination, the application of this approach on aqueous samples is problematic. In this work, the sample is treated in a vial with 2,2-dimethoxypropane (DMP) under… Read Abstract

• Stem Cells. 2015 Sep Brief Report: Human Mesenchymal Stem-Like Cells Facilitate Floating Tumorigenic Cell Growth via Glutamine-Ammonium Cycle.

  How mesenchymal stem cells (MSCs) promote tumor growth remains incompletely understood. Here, we show that mesenchymal stem-like cells (MSLCs) are commonly present in malignant pleural effusion or ascites of cancer patients, where they directly interact with tumor cells. Chemokines and chemokine receptors, especially the CCL2/CCR2 pathway, are involved in this interaction. As a result, MSLCs… Read Abstract

• International Journal of Food Microbiology. 2014 May New insights into the advantages of ammonium as a winemaking nutrient.

  Nitrogen limitation is the most common cause for stuck or sluggish fermentation in winemaking, and it is usually dealt with by supplementing grape juice with either ammonium salts or organic nutrients. These practices have a direct impact on both fermentation kinetics and the sensorial features of the final product. The aim of this work is… Read Abstract

• Science of the Total Environment. 2019 Jan Development of a polydimethylsiloxane-thymol/nitroprusside composite based sensor involving thymol derivatization for ammonium monitoring in water samples.

  This report describes a polydimethylsiloxane (PDMS)-thymol/nitroprusside delivery composite sensor for direct monitoring of ammonium in environmental water samples. The sensor is based on a PDMS support that contains the Berthelot’s reaction reagents. To prepare the PDMS-thymol/nitroprusside composite discs, thymol and nitroprusside have been encapsulated in the PDMS matrix, forming a reagent release support which significantly… Read Abstract

• Proceedings of the National Academy of Sciences of the United States of America . 2014 Jul Direct observation of electrogenic NH4(+) transport in ammonium transport (Amt) proteins.

  Ammonium transport (Amt) proteins form a ubiquitous family of integral membrane proteins that specifically shuttle ammonium across membranes. In prokaryotes, archaea, and plants, Amts are used as environmental NH4(+) scavengers for uptake and assimilation of nitrogen. In the eukaryotic homologs, the Rhesus proteins, NH4(+)/NH3 transport is used instead in acid-base and pH homeostasis in kidney… Read Abstract

• Revista Brasileira de Ciência do Solo. 2018 Dec Acid Ammonium Citrate as P Extractor for Fertilizers of Varying Solubility

  There are several globally accepted methods to chemically characterize P-fertilizers, but not all are suitable to predict the agronomic efficiency of the P sources in terms of plant nutrition. Our aim was to investigate the performance of P extractors for fertilizers, investigating the consistency of different methods for P sources of varying properties and the… Read Abstract

• Journal of Experimental Botany. 2017 Mar Ammonium as a signal for physiological and morphological responses in plants

  Ammonium is a major inorganic nitrogen source for plants. At low external supplies, ammonium promotes plant growth, while at high external supplies it causes toxicity. Ammonium triggers rapid changes in cytosolic pH, in gene expression, and in post-translational modifications of proteins, leading to apoplastic acidification, co-ordinated ammonium uptake, enhanced ammonium assimilation, altered oxidative and phytohormonal… Read Abstract

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