Calcium Citrate Malate USP Fine Granular

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• J Orthop Case Rep. 2018 Jul A Randomized Open-Label Clinical Study Comparing the Efficacy, Safety, and Bioavailability of Calcium Lysinate with Calcium Carbonate and Calcium Citrate Malate in Osteopenia Patients

  Introduction: Many factors influence bone health, but osteoporosis is viewed as a calcium deficiency disorder in which bone is resorbed to maintain the serum calcium levels. Dietary calcium supplements have been recommended for the prevention of osteoporosis in the elderly. Many forms of dietary calcium supplements are widely available in market, but products containing calcium citrate… Read Abstract

• Altern Med Rev. 1999 Sep Comparative absorption of calcium sources and calcium citrate malate for the prevention of osteoporosis

  Anthropologically speaking, humans were high consumers of calcium until the onset of the Agricultural Age, 10,000 years ago. Current calcium intake is one-quarter to one-third that of our evolutionary diet and, if we are genetically identical to the Late Paleolithic Homo sapiens, we may be consuming a calcium-deficient diet our bodies cannot adjust to by… Read Abstract

• Adv Food Nutr Res. 2008 Jan The health benefits of calcium citrate malate: a review of the supporting science

  There has been considerable investigation into the health benefits of calcium citrate malate (CCM) since it was first patented in the late 1980s. This chapter is a comprehensive summary of the supporting science and available evidence on the bioavailability and health benefits of consuming CCM. It highlights the important roles that CCM can play during… Read Abstract

• J Nutr. 1994 Aug Supplementation trials with calcium citrate malate: evidence in favor of increasing the calcium RDA during childhood and adolescence

  The vast majority of peak adult bone mass is accumulated by the time longitudinal growth is complete. As peak bone mass is an important determinant of future fracture risk, the goal of the current calcium recommended dietary allowance during youth is to provide a calcium intake that allows individuals to reach their full genetic potential… Read Abstract

• Poult Sci. 2002 Aug An investigation of calcium citrate-malate as a calcium source for young broiler chicks

  Two experiments were conducted to compare a sample of calcium citrate-malate (CC-M) with a sample of commercial-grade limestone in starting broiler chick diets. In the first experiment, with 0.7 or 0.9% calcium from limestone or CC-M, no differences in bone development (dry fat-free tibia, tibia weight, tibia ash, or tibia calcium) were observed due to… Read Abstract

• Int J Biol Macromol. 2013 Jul Assessment the levels of tartrate-resistant acid phosphatase (TRAP) on mice fed with eggshell calcium citrate malate

  Optimized conditions were obtained by one-factor-at-a-time test (OFAT) and ternary quadratic regression orthogonal composite design (TQROCD) respectively. By pulse electric fields (PEF) technology, the process of eggshell calcium citrate malate (ESCCM), eggshell calcium citrate (ESCC) and eggshells calcium malate (ESCM) were comprehensive compared. The levels of tartrate-resistant acid phosphatase (TRAP) and the bioavailability on mice… Read Abstract

• Food Chem. 2018 Apr Bioaccessibility of four calcium sources in different whey-based dairy matrices assessed by in vitro digestion

  Numerous calcium sources are available to enrich food, but their behavior during digestion is still unknown. This study focused on the influence of the gastro-intestinal pH, the food structure and the calcium source on the bioaccessibility of the nutrient. Four calcium sources were studied: calcium carbonate, calcium citrate malate, calcium phosphate and calcium bisglycinate. These… Read Abstract

• J Nutr. 1990 Aug Effect of calcium citrate-malate on skeletal development in young, growing rats

  It has been previously demonstrated that calcium from calcium citrate-malate (CCM), a mixture of calcium, citric acid and malic acid, is better-absorbed than calcium from calcium carbonate (CaCO3) in humans and in rats. It was of interest to determine if this differential in absorption would result in differences in bone development under chronic feeding conditions.… Read Abstract

• J Am Coll Nutr. 1996 Jun Calcium absorption from apple and orange juice fortified with calcium citrate malate (CCM)

  Objective: Determine calcium (Ca) absorption from Ca fortified orange and apple juice. Methods: Absorbability was assessed by measuring 45Ca absorption in healthy women (mean age 57 years, n = 57/group) and whole body 47Ca retention in adult female beagle dogs (n = 6/group) and young adult male rats (n = 6/group). Women received 6.24 mmol (250 mg)… Read Abstract

• Pnas. 2014 Jul Excited-state structural dynamics of a dual-emission calmodulin-green fluorescent protein sensor for calcium ion imaging

  Fluorescent proteins (FPs) have played a pivotal role in bioimaging and advancing biomedicine. The versatile fluorescence from engineered, genetically encodable FP variants greatly enhances cellular imaging capabilities, which are dictated by excited-state structural dynamics of the embedded chromophore inside the protein pocket. Visualization of the molecular choreography of the photoexcited chromophore requires a spectroscopic technique… Read Abstract

• Nutrition Reviews. 2012 Jul Role of calcium during pregnancy: maternal and fetal needs

  Although the demand for additional calcium during pregnancy is recognized, the dietary reference intake for calcium was lowered for pregnant women in 1997 to amounts recommended for nonpregnant women (1,000 mg/day), and recently (November 2010) the Institute of Medicine report upheld the 1997 recommendation. It has been frequently reported that women of childbearing age do… Read Abstract

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