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Home › Related Articles › New perspectives in oral peptide delivery
Drug Discovery Today. 2021 Apr

New perspectives in oral peptide delivery

Abstract:

Owing to their structural diversity, peptides are a unique source of innovative active ingredients. However, their development has been challenging because of their disadvantageous pharmacokinetic (PK) properties. Over the past decade, many attempts have been made to improve the oral bioavailability of peptide drugs. In this review, we highlight the most recent and promising techniques aimed at the improvement of the oral bioavailability of peptides. The most recent findings will influence future approaches of pharmaceutical companies in the development of new, more efficient, and safer orally delivered peptides.

PMID 33497830  /  Alessandra T. Zizzari, Dimanthi Pliatsika, Flavio M.Gall, Thomas Fischer, Rainer Riedl

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